F - Five years or less since reaction
A - Anaphylaxis or angioedema
S - Severe cutaneous adverse reaction
T - Treatment required for reaction

SCORE:

Next Steps:



PEN-FAST - Penicillin Allergy Risk Tool

Clinical decision rule for point-of-care risk assessment of patient-reported penicillin allergies.

Details:

Only patients who report a penicillin allergy are eligible for PEN-FAST.

A severe cutaneous adverse drug reaction includes Stevens-Johnson syndrome, toxic epidermal necrolysis, DRESS, or acute generalized exanthematous pustulosis. Acute interstitial nephritis, drug induced liver injury, serum sickness and isolated drug fever are not counted.

Risk of a positive penicillin allergy test

  • 0 points – Neglibable risk of positive penicillin allergy test
  • 1-2 points – Low risk of positive penicillin allergy test 5%
  • 3 points – Moderate risk of positive penicillin allergy test 20%
  • 4 points – High risk of positive penicillin allergy test 50%